Immune Checkpoint Recombinant Proteins
Human CD30 Ligand Recombinant Protein (mFc-His Tag) (HDPT0038)
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- SKU:
- HDPT0038
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human CD30 Ligand Recombinant Protein (mFc-His Tag)
| Description: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. |
| Product name: | Human CD30 Ligand Recombinant Protein (mFc-His Tag) |
| Synonyms: | CD30-L,CD153,TNFSF8,CD30L,CD30LG,CD153 antigen,CD30 antigen ligand,CD30 Ligand |
| Type: | protein |
| Size: | 50 µg |
| Name: | CD30 Ligand |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | ELISA |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Mouse Fc and C-6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | mFc（Pro99-Lys330）+CD30 Ligand（Gln63-Asp234）+6×His |
| Gene ID: | 944 |
| Uniprot: | P32971 |
| Molecular Weight: | 48.0 kDa |
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