Human CD28 Monoclonal Antibody (FITC Conjugated) [CD28.2](AGEL2020)
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](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/12925/16977/human-cd28-monoclonal-antibody-fitc-conjugated-cd28.2agel2020__69802__92918.1706270194.jpg?c=1 "Human CD28 Monoclonal Antibody (FITC Conjugated) [CD28.2](AGEL2020)")
- SKU:
- AGEL2020
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FC
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a,k
- Clone:
- CD28.2
- Conjugation:
- FITC
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/12925/16977/human-cd28-monoclonal-antibody-fitc-conjugated-cd28.2agel2020__69802__92918.1706270194.jpg?c=1&imbypass=on "Human CD28 Monoclonal Antibody (FITC Conjugated) [CD28.2](AGEL2020)")
Description
| Antibody Name: | Human CD28 Monoclonal Antibody (FITC Conjugated) |
| Antibody Code: | AGEL2020 |
| Size: | 50 Tests |
| Clone: | CD28.2 |
| Synonyms: | PAS2,MNS,HGpMiX,GYPA,GPSAT |
| Host Species: | Mouse |
| Species Reactivity: | Human |
| Applications: | FC |
| Concentration: | 5uL |
| Isotype: | IgG2a,k |
| Conjugation: | FITC |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
| Gene ID: | 940 |
| Uniprot: | P10747 |
| Background: | CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation. |
 | Human peripheral blood lymphocytes are stained with Anti-Human CD28 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |
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