Cell Death Recombinant Proteins

Human CD27/TNFRSF7 Recombinant Protein (RPES5085)

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SKU:
RPES5085
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human CD27/TNFRSF7 Recombinant Protein

CD27 antigen is also known as CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7; T14 and TNFRSF7. In humans; it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70; and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.

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