Cell Biology Recombinant Proteins

Human CD155/PVR/NECL5 Recombinant Protein (RPES0460)

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RPES0460

Description

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Human CD155/PVR/NECL5 Recombinant Protein

Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (?; β; ?; and ?) with identical extracellular domains.

Product Name:Human CD155/PVR/NECL5 Recombinant Protein (RPES0460)
Product Code:RPES0460
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Poliovirus Receptor, Nectin-Like Protein 5, NECL-5, CD155, PVR, PVS
Accession:P15151
Sequence:Trp21-Asn343
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human NECL5 is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a Fc tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:62.2 kDa
AP Mol Mass:80-120 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS;pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
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