Human CD123 Monoclonal Antibody (Alexa Fluor 488 Conjugated) [6H6](AGEL0445)

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SKU:
AGEL0445
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
6H6
Conjugation:
AF 488
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Human CD123 Monoclonal Antibody (Alexa Fluor 488 Conjugated)
Antibody Code:AGEL0445
Size:50 Tests
Clone:6H6
Synonyms:IL-3Rα, IL-3 Receptor alpha
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:5uL
Isotype:IgG1
Conjugation:Alexa Fluor 488
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:3563
Uniprot:P26951
Background:CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Mouse CD19 Monoclonal Antibody (FITC Conjugated)Human peripheral blood lymphocytes are stained with Anti-Human CD123 Monoclonal Antibody (Alexa Fluor 488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
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