Description
Antibody Name: | Human CD11a Monoclonal Antibody (FITC Conjugated) |
Antibody Code: | AGEL0962 |
Size: | 50 Tests |
Clone: | TS1/22.1.1.13 |
Synonyms: | Integrin alpha-L,Itgal,CD11 antigen-like family member A,LFA-1A,Lymphocyte antigen 15,Ly-15,CD11a |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | FITC |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 3683 |
Uniprot: | P20701 |
Background: | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
Human peripheral blood lymphocytes are stained with Anti-Human CD11a Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |