Immune Checkpoint Recombinant Proteins

Human CCR7 Recombinant Protein (hFc Tag) (HDPT0225)

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SKU:
HDPT0225
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human CCR7 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
Product name:Human CCR7 Recombinant Protein (hFc Tag)
Synonyms:BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1
Type:protein
Size:50 µg
Name:CCR7
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CCR7(Gln25-Trp59)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:P32248
Molecular Weight:29.37 kDa
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