Human Cathepsin Z Recombinant Protein (RPES4454)
- SKU:
- RPES4454
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Cathepsin Z Recombinant Protein
Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.
| Product Name: | Human Cathepsin Z Recombinant Protein (RPES4454) |
| Product Code: | RPES4454 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ |
| Accession: | Q9UBR2 |
| Sequence: | Gly24-Val303 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 32.5 kDa |
| AP Mol Mass: | 37 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM HAc-NaAc; 150mM NaCl; pH 4.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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