Human CAPN6 / Calpain 6 ELISA Kit

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SKU:
HUFI01844
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9Y6Q1
Sensitivity:
0.938ng/ml
Range:
1.563-100ng/ml
ELISA Type:
Sandwich
Synonyms:
CAPN6, Calpain-like protease X-linked, Calpamodulin, CalpM
Reactivity:
Human
Research Area:
Cell Biology

Description

Human CAPN6 / Calpain 6 ELISA

Calpains are a diverse family of calcium-dependent, cysteine proteases. Calpains have been linked to neurodegenerative diseases, since their activation can be promoted by calcium influx and oxidative stress. Calpain 6 is abundantly expressed in the placenta. Calpain 6 lacks important active site residues, indicating that it is proteolytically inactive. The protein may be involved in tumor development by compromising apoptosis and promoting angiogenesis. Leiomyosarcoma and leiomyoma are two types of cancer that can be associated with CAPN6. Integrin Pathway and ERK Signaling are two related pathways influenced by CAPN6.

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