Human Calcitonin/CALCA Recombinant Protein (RPES3910)
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- SKU:
- RPES3910
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Calcitonin/CALCA Recombinant Protein
Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+); opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals; as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
| Product Name: | Human Calcitonin/CALCA Recombinant Protein (RPES3910) |
| Product Code: | RPES3910 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1 |
| Accession: | P01258 |
| Sequence: | Ala26-Asn141 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Calcitonin is produced by our Mammalian expression system and the target gene encoding Ala26-Asn141 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 13.8 kDa |
| AP Mol Mass: | 16 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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system_update_altDatasheetHuman Calcitonin/CALCA Recombinant Protein Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains:
