Human CA5A/CA-VA Recombinant Protein (RPES2596)
- SKU:
- RPES2596
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human CA5A/CA-VA Recombinant Protein
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of the alpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt).
| Product Name: | Human CA5A/CA-VA Recombinant Protein (RPES2596) |
| Product Code: | RPES2596 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | CA5,CA5AD,CA5D,Carbonic Anhydrase VA,CAV,CAVA,GS1-21A4.1 |
| Accession: | NP_001730.1 |
| Sequence: | Ala 40-Ser 305 |
| Fusion tag: | C-His |
| Activity: | Measured by its esterase activity. The specific activity is >500 pmoles/min/µg. |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the mature form of human CA5A (NP_001730.1) (Ala 40-Ser 305) was fused with an Met at N-terminus and a polyhistide tag at the C-terminus. |
| Purity: | > 96 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 31.6 kDa |
| AP Mol Mass: | 33 kDa |
| Formulation: | Lyophilized from sterile 50mM NaAc, 50mM NaCl, 0.05% Brij 35, pH 5.0 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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