Immunology Recombinant Proteins
Human BTN3A3 Recombinant Protein (RPES5115)
- SKU:
- RPES5115
Description
Human BTN3A3 Recombinant Protein
Tumor necrosis factor receptor superfamily; member 19 (TNFRSF19); also known as TAJ-alpha or TROY; is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members; and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism; and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation; comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family; and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
| Product Name: | Human BTN3A3 Recombinant Protein (RPES5115) |
| Product Code: | RPES5115 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | Butyrophilin subfamily 3 member A3,BTN3A3,BTF3,BTN3.3 |
| Accession: | O00478-1 |
| Sequence: | Met 1-Trp248 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human BTN3A3 (O00478-1) (Met1-Trp248) was fused with Fc region of mouse IgG at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 50 kDa |
| AP Mol Mass: | 53 in SDS-PAGE under reducing conditions. |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Immunology |
Related Products
Human BTN3A3 Recombinant Protein (RPES1375)
Immunology Recombinant Proteins
Human BTN3A3 Recombinant Protein (His Tag)
Human B2M Recombinant Recombinant Protein (RPPB2842)
