Human BIM / BCL2L11 ELISA Kit

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SKU:
HUFI02254
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O43521
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
Bcl2L11, BAM, BIM, BOD, BimL, BimEL, BIM Long
Reactivity:
Human
Research Area:
Cell Death

Description

Human BIM / BCL2L11 ELISA Kit

BIM / BCL2L11 belongs to the BCL-2 protein family, which acts as a pro-apoptotic regulator in a wide variety of cellular activities. Expression of BIM / BCL2L11 gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. BIM / BCL2L11 is also an essential initiator of apoptosis in thymocyte-negative selection. Diseases associated with BIM / BCL2L11 include Interleukin-7 Receptor Alpha Deficiency and Autoimmune Lymphoproliferative Syndrome.

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