Description
| Product Name: | Human BCL7C Recombinant Protein |
| Product Code: | RPPB5853 |
| Size: | 10µg |
| Species: | Human |
| Target: | BCL7C |
| Synonyms: | B-Cell CLL/Lymphoma 7C, B-Cell CLL/Lymphoma 7 Protein Family Member C, BCL7C. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | BCL7C protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
B-cell CLL/lymphoma 7C (BCL7C) is identified by the likeness of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene which is directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of the BCL7C gene has not been determined yet.
BCL7C Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 240 amino acids (1-217 a.a) and having a molecular mass of 25.9kDa (Molecular size on SDS-PAGE will appear higher).BCL7C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Bcl-7C: May play an anti-apoptotic role. Belongs to the BCL7 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16p11 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
| UniProt Code: | Q8WUZ0 |
| NCBI GenInfo Identifier: | 296439426 |
| NCBI Gene ID: | 9274 |
| NCBI Accession: | Q8WUZ0.3 |
| UniProt Secondary Accession: | Q8WUZ0,O43770, Q6PD89 |
| UniProt Related Accession: | Q8WUZ0 |
| Molecular Weight: | 26,422 Da |
| NCBI Full Name: | B-cell CLL/lymphoma 7 protein family member C |
| NCBI Synonym Full Names: | BCL tumor suppressor 7C |
| NCBI Official Symbol: | BCL7C�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | B-cell CLL/lymphoma 7 protein family member C |
| UniProt Protein Name: | B-cell CLL/lymphoma 7 protein family member C |
| UniProt Synonym Protein Names: | |
| Protein Family: | B-cell CLL/lymphoma 7 protein family |
| UniProt Gene Name: | BCL7C�� |
| UniProt Entry Name: | BCL7C_HUMAN |