Human BAK1 / BCL2-antagonist / killer 1 isoform 1 ELISA Kit

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SKU:
HUFI02248
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q16611
Sensitivity:
0.375ng/ml
Range:
0.625-40ng/ml
ELISA Type:
Sandwich
Synonyms:
BAK1, BAK, BCL2L7, Apoptosis regulator BAK, BAK-LIKE, BAKMGC3887, BCL2-antagonist, killer 1, Bcl2-L-7, bcl2-L-7, BCL2L7bcl-2 homologous antagonist, killer, BCL2-like 7 protein, Bcl-2-like protein 7, CDN1, MGC117255, pro-apoptotic protein BAK
Reactivity:
Human
Research Area:
Cell Death

Description

Human BAK1 / BCL2-antagonist / killer 1 isoform 1 ELISA Kit

BAK1 / BCL2-antagonist / killer 1 isoform 1 belongs to the BCL2 protein family, and acts as an apoptotic regulator. BAK1 / BCL2-antagonist / killer 1 isoform 1 localizes to mitochondria, accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. BAK1 / BCL2-antagonist / killer 1 isoform 1 also induces apoptosis by interacting with the tumor suppressor P53 after exposure to cell stress. Diseases associated with BAK1 / BCL2-antagonist / killer 1 isoform 1 include Absolute Glaucoma and Keratoacanthoma.

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