Cell Biology Recombinant Proteins
Human ASGR1/ASGPR1 Recombinant Protein (RPES3554)
- SKU:
- RPES3554
Description
Human ASGR1/ASGPR1 Recombinant Protein
ASGR1 is a subunit of the asialoglycoprotein receptor. ASGR1 is a transmembrane protein that controls endocytosis and lysosomal breakdown of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues, which is critical for glycoprotein homeostasis. The asialoglycoprotein receptor serves as a target for liver-specific drug delivery, and it may aid viral infection in the liver by many pathogens, including hepatitis B. The asialoglycoprotein receptor is a heteropolymeric protein with two distinct genes encoding its major and minor components. Hepatitis is a condition that is associated with ASGR1. Protein metabolism and transport to the Golgi and subsequent modification are two examples of ASGR1 related pathways. Human ASGR1/ASGPR1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human ASGR1/ASGPR1 Recombinant Protein (RPES3554) |
| Product Code: | RPES3554 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Asialoglycoprotein Receptor 1, ASGP-R 1, ASGPR 1, C-Type Lectin Domain Family 4 Member H1, Hepatic Lectin H1, HL-1, ASGR1, CLEC4H1 |
| Accession: | P07306 |
| Sequence: | Gln62-Ile291 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 27.4 kDa |
| AP Mol Mass: | 38 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Cell Biology |
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