Human Arylsulfatase A/ARSA Recombinant Protein (RPES3022)
- SKU:
- RPES3022
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human Arylsulfatase A/ARSA Recombinant Protein
Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.
| Product Name: | Human Arylsulfatase A/ARSA Recombinant Protein (RPES3022) |
| Product Code: | RPES3022 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Arylsulfatase A, ASA, Cerebroside-Sulfatase, ARSA |
| Accession: | P15289 |
| Sequence: | Arg19-Ala507 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 52.9 kDa |
| AP Mol Mass: | 55 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |