Cell Death Recombinant Proteins
Human APLP Recombinant Protein (RPES4294)
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- SKU:
- RPES4294
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
Description
system_update_altDatasheet
Human APLP Recombinant Protein
APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
| Product Name: | Human APLP Recombinant Protein (RPES4294) |
| Product Code: | RPES4294 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | Amyloid-like protein 1, APLP, APLP-1, C30, APLP1 |
| Accession: | P51693-1 |
| Sequence: | Met 1-Glu580 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human APLP1 (P51693-1) (Met1-Glu580) was expressed with a polyhistidine tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 61.9 kDa |
| AP Mol Mass: | 67-77 kDa |
| Formulation: | Lyophilized from sterile PBS, PH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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