Human APCS/SAP Recombinant Protein (RPES4887)

(No reviews yet) Write a Review
SKU:
RPES4887
Product Type:
Recombinant Protein
Species:
Human

Description

system_update_altDatasheet

Human APCS/SAP Recombinant Protein

Serum Amyoid P Component (SAP) is a monomeric 25 kDa secreted serum glycoprotein that belongs to the pentraxins family. The members of pentaxin superfamily be characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. SAP is a non-fibrillar component; it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. SAP scavenge nuclear material released from damaged circulating cells. It has been proposed that SAP may function as an opsonin for a variety of ligands including autoantigens; apoptotic cells; chromatin and micro-organisms.

View AllClose

0 Reviews

View AllClose