HTR6 Polyclonal Antibody
- SKU:
- CAB10671
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HTR6 Polyclonal Antibody |
| Product Code: | CAB10671 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 321-440 of human HTR6 (NP_000862.1). |
| Sequence: | PLFMR DFKRA LGRFL PCPRC PRERQ ASLAS PSLRT SHSGP RPGLS LQQVL PLPLP PDSDS DSDAG SGGSS GLRLT AQLLL PGEAT QDPPL PTRAA AAVNF FNIDP AEPEL RPHPL GIPTN |
| Synonyms: | 5-HT6, 5-HT6R |
| Calculated MW: | 47kDa |
| Observed MW: | Refer to figures |
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