Description
system_update_alt Datasheet
Product Name: | HSP90 Alpha Antibody |
Product Sku: | CPAB0289 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human HSP9A mAb, is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP9A amino acids 1-732 purified from Ecoli. |
Clone: | P4F10AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA, Immunohistochemistry |
Purification Method: | HSP90A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration. |
Synonyms: | HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, HSP90A, HSP90N, HSPCAL1, HSPCAL4, FLJ31884, Heat shock protein HSP 90-alpha, Renal carcinoma antigen NY-REN-38, HSP 86, HSP90AA1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |