Description
| Product Name: | HRPT2 / CDC73 Monoclonal Antibody |
| Product Code: | CAB23565 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC3131 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, caco-2, RAW264.7 |
| Cellular Location: | Nucleus |
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
| Immunogen: | Recombinant protein of human HRPT2 / CDC73. |
| Sequence: | Email for sequence |
| Synonyms: | HYX, FIHP, HPTJT, HRPT1, HRPT2, C1orf28 |
| Calculated MW: | 61kDa |
| Observed MW: | 61kDa |