HOXA5 Polyclonal Antibody
- SKU:
- CAB20730
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HOXA5 Polyclonal Antibody |
| Product Code: | CAB20730 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | nucleus |
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-170 of human HOXA5 (NP_061975.2). |
| Sequence: | GSGHF GSGER ARSYA ASASA APAEP RYSQP ATSTH SPQPD PLPCS AVAPS PGSDS HHGGK NSLSN SSGAS ADAGS THISS REGVG TASGA EEDAP ASSEQ ASAQS EPSPA P |
| Synonyms: | HOX1, HOX1C, HOX1.3 |
| Calculated MW: | 29kDa |
| Observed MW: | Refer to figures |
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