HNRNPD Monoclonal Antibody
- SKU:
- CAB23281
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | HNRNPD Monoclonal Antibody |
| Product Code: | CAB23281 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59955 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, NIH/3T3, C6 |
| Cellular Location: | Cytoplasm, Nucleus |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
| Immunogen: | Recombinant protein of human HNRNPD. |
| Sequence: | MSEEQ FGGDG AAAAA TAAVG GSAGE QEGAM VAATQ GAAAA AGSGA GTGGG TASGG TEGGS AESEG AKIDA SKNEE DEGHS NSSPR HSEAA TAQRE EWKMF IGGLS WDTTK KDLKD YFSKF GEVVD CTLKL DPITG RSRGF GFVLF KESES VDKVM DQKEH KLNGK VIDPK RAKAM KTKEP VKKIF VGGLS PDTPE EKIRE YFGGF GEVES IELPM DNKTN KRRGF CFITF KEEEP VKKIM EKKYH NVGLS KCEIK VAMSK EQYQQ QQQWG SRGGF AGRAR GRGGD QQSGY GKVSR RGGHQ NSYKP Y |
| Synonyms: | P37, AUF1, AUF1A, HNRPD, hnRNPD0 |
| Calculated MW: | 38kDa |
| Observed MW: | 37-48kDa |
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