HK1 Polyclonal Antibody

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SKU:
CAB0546
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:HK1 Polyclonal Antibody
Product Code:CAB0546
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples:293T
Cellular Location:Mitochondrion outer membrane

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human HK1 (NP_000179.2).
Sequence:KKIDK YLYAM RLSDE TLIDI MTRFR KEMKN GLSRD FNPTA TVKML PTFVR SIPDG SEKGD FIALD LGGSS FRILR VQVNH EKNQN VHMES EVYDT PENIV HGSGS QLFDH VAECL GDFME KRKIK DKKLP VGFTF SFPCQ QSKID EAILI TWTKR FKASG VEGAD VVKLL NKAIK KRGDY DANIV AVVND TVGTM MTCGY DDQHC EVGLI IGTGT NACYM EELRH IDLVE GDEGR MCINT EWGAF GDDGS LEDIR TEFDR EIDRG SLNPG KQLFE KMVSG M
Synonyms:HK, HKD, HKI, HXK1, NMSR, RP79, HMSNR, HK1-ta, HK1-tb, HK1-tc, NEDVIBA, hexokinase
Calculated MW:102kDa
Observed MW:110kDa
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