HK1 Monoclonal Antibody [P4D7AT] (CPAB0134)
![HK1 Monoclonal Antibody [P4D7AT] (CPAB0134)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58360/63542/hk1-monoclonal-antibody-p4d7at-cpab0134__67686__69564.1706534984.jpg?c=1 "HK1 Monoclonal Antibody [P4D7AT] (CPAB0134)")
- SKU:
- CPAB0134
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- P4D7AT
- Applications:
- WB
- Applications:
- ELISA
![HK1 Monoclonal Antibody [P4D7AT] (CPAB0134)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58360/63542/hk1-monoclonal-antibody-p4d7at-cpab0134__67686__69564.1706534984.jpg?c=1&imbypass=on "HK1 Monoclonal Antibody [P4D7AT] (CPAB0134)")
Description
system_update_alt Datasheet
| Product Name: | HK1 Antibody |
| Product Sku: | CPAB0134 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human Hexokinase-1 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Hexokinase-1 amino acids 1-917 purified from Ecoli. |
| Clone: | P4D7AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | Hexokinase-1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of HXK1 results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. |
| Synonyms: | Hexokinase-1, EC 2.7.1.1, Hexokinase type I, HK I, Brain form hexokinase, HK1-ta, HK1-tb, HXK1, HK1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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