Description
Product Name: | HK1 Monoclonal Antibody |
Product Code: | CAB23524 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC51068 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293T, Mouse brain |
Cellular Location: | Mitochondrion outer membrane |
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human HK1 (NP_000179.2). |
Sequence: | KIDKY LYAMR LSDET LIDIM TRFRK EMKNG LSRDF NPTAT VKMLP TFVRS IPDGS EKGDF IALDL GGSSF RILRV QVNHE KNQNV HMESE VYDTP ENIVH GSGSQ LFDHV AECLG DFMEK RKIKD KKLPV GFTFS FPCQQ SKIDE AILIT WTKRF KASGV EGADV VKLLN KAIKK RGDYD ANIVA VVNDT VGTMM TCGY |
Synonyms: | HK, HKD, HKI, HXK1, NMSR, RP79, HMSNR, HK1-ta, HK1-tb, HK1-tc, NEDVIBA, hexokinase |
Calculated MW: | 102kDa |
Observed MW: | 102kDa |