Name: HBsAgA Monoclonal Antibody (CPAB0709)
SKU: CPAB0709
Availability: OutOfStock

HBsAgA Monoclonal Antibody (CPAB0709)

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SKU:

CPAB0709

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Reactivity:

Virus

Description

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Purification Method:
Isotype:
Background:	Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
Synonyms:
Storage Buffer:	Store at -20°C.