HADHA Monoclonal Antibody (CAB24608)
- SKU:
- CAB24608
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | HADHA Monoclonal Antibody |
| Product Code: | CAB24608 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61203 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:1000-1:3000, IHC-P 1:50-1:400, IF/ICC 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, 293T |
| Cellular Location: | Mitochondrion |
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 545-763 of human HADHA (NP_000173.2). |
| Sequence: | FYTTR CLAPM MSEVI RILQE GVDPK KLDSL TTSFG FPVGA ATLVD EVGVD VAKHV AEDLG KVFGE RFGGG NPELL TQMVS KGFLG RKSGK GFYIY QEGVK RKDLN SDMDS ILASL KLPPK SEVSS DEDIQ FRLVT RFVNE AVMCL QEGIL ATPAE GDIGA VFGLG FPPCL GGPFR FVDLY GAQKI VDRLK KYEAA YGKQF TPCQL LADHA NSPNK KFYQ |
| Synonyms: | GBP, ECHA, HADH, LCEH, MTPA, LCHAD, TP-ALPHA |
| Calculated MW: | 83kDa |
| Observed MW: | 75kDa |
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