Description
| Product Name: | Grp94 Polyclonal Antibody |
| Product Code: | CAB21635 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum lumen, Melanosome |
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human Grp94 (NP_003290.1). |
| Sequence: | ESEKT KESRE AVEKE FEPLL NWMKD KALKD KIEKA VVSQR LTESP CALVA SQYGW SGNME RIMKA QAYQT GKDIS TNYYA SQKKT FEINP RHPLI RDMLR R |
| Synonyms: | ECGP, GP96, TRA1, GRP94, HEL35, HEL-S-125m |
| Calculated MW: | 92kDa |
| Observed MW: | Refer to figures |