GRIN3A Polyclonal Antibody
- SKU:
- CAB10689
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | GRIN3A Polyclonal Antibody |
| Product Code: | CAB10689 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, postsynaptic density, synapse |
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 986-1115 of human GRIN3A (NP_597702.2). |
| Sequence: | SFIEE KQQHF KTKRV EKRSN VGPRQ LTVWN TSNLS HDNRR KYIFS DEEGQ NQLGI RIHQD IPLPP RRREL PALRT TNGKA DSLNV SRNSV MQELS ELEKQ IQVIR QELQL AVSRK TELEE YQRTS RTCES |
| Synonyms: | NR3A, GluN3A, NMDAR-L, NMDAR3A |
| Calculated MW: | 125kDa |
| Observed MW: | Refer to figures |
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