Glutamine Synthetase (GLUL) Polyclonal Antibody
- SKU:
- CAB21822
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Glutamine Synthetase (GLUL) Polyclonal Antibody |
| Product Code: | CAB21822 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain, Rat liver, Rat brain |
| Cellular Location: | Cytoplasm, Mitochondrion |
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-373 of human Glutamine Synthetase (GLUL) (NP_002056.2). |
| Sequence: | MTTSA SSHLN KGIKQ VYMSL PQGEK VQAMY IWIDG TGEGL RCKTR TLDSE PKCVE ELPEW NFDGS STLQS EGSNS DMYLV PAAMF RDPFR KDPNK LVLCE VFKYN RRPAE TNLRH TCKRI MDMVS NQHPW FGMEQ EYTLM GTDGH PFGWP SNGFP GPQGP YYCGV GADRA YGRDI VEAHY RACLY AGVKI AGTNA EVMPA QWEFQ IGPCE GISMG DHLWV ARFIL HRVCE DFGVI ATFDP KPIPG NWNGA GCHTN FSTKA MREEN GLKYI EEAIE KLSKR HQYHI RAYDP KGGLD NARRL TGFHE TSNIN DFSAG VANRS ASIRI PRTVG QEKKG YFEDR RPSAN CDPFS VTEAL IRTCL LNETG DEPFQ YKN |
| Synonyms: | GS, GLNS, PIG43, PIG59 |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |
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Glutamine Synthetase (GLUL) Monoclonal Antibody
OverviewProduct Name:Glutamine Synthetase (GLUL) Monoclonal AntibodyProduct Code:CAB21856Reactivity:Human, Mouse, RatApplications:
