GenieFluor Violet 450 Anti-Mouse CD45.2 Antibody [104.2] (AGEL3362)
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- SKU:
- AGEL3362
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- Mouse IgG2a, k
- Clone:
- 104.2
- Conjugation:
- AFViolet 450
Description
| Product Name: | AFViolet 450 Anti-Mouse CD45.2 Antibody [104.2] |
| Product Code: | AGEL3362 |
| Size: | 25ug, 100ug |
| Clone No: | 104.2 |
| Synonyms: | Ly-5.2, LCA |
| Reactivity: | Mouse |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG2a, κ |
| Isotype Control: | EV450 Mouse IgG1, κ Isotype Control [MOPC-21] |
| Conjugation: | AFViolet 450 |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | GenieFluor Violet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 19264 |
| Background Information: | CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. |
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