Description
Product Name: | G6PC2 Polyclonal Antibody |
Product Code: | CAB20731 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human G6PC2 (NP_066999.1). |
Sequence: | MDFLH RNGVL IIQHL QKDYR AYYTF LNFMS NVGDP RNIFF IYFPL CFQFN QTVGT KMIWV AVIGD WLNLI FKWIL FGHRP YWWVQ ETQIY PNHSS PCLEQ |
Synonyms: | IGRP |
Calculated MW: | 41kDa |
Observed MW: | Refer to figures |