FITC Anti-Mouse CD366/Tim-3 Antibody [RMT3-23] (AGEL3378)

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SKU:
AGEL3378
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
RMT3-23
Conjugation:
FITC

Description

Product Name:FITC Anti-Mouse CD366/Tim-3 Antibody [RMT3-23]
Product Code:AGEL3378
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RMT3-23
Synonyms:TIM3, TIMD3, HAVcr-2, TIMD-3
Reactivity:Mouse
Host Species:Rat
Applications:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control [2A3]
Conjugation:FITC
Applications:FCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:84868
Swissprot:Q8VIM0
Background Information:CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
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