FITC Anti-Mouse CD3ε Antibody [145-2C11]
- SKU:
- AGEL2201
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Armenian Hamster
- Isotype:
- Armenian Hamster IgG
- Clone:
- 145-2C11
- Conjugation:
- FITC
Description
| Product Name: | FITC Anti-Mouse CD3ε Antibody [145-2C11] |
| Product Code: | AGEL2201 |
| Clone No: | 145-2C11 |
| Synonyms: | T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Applications: | FCM |
| Isotype: | Armenian Hamster IgG |
| Isotype Control: | FITC Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2549) |
| Conjugation: | FITC |
| Form: | Liquid |
| Fluorescent Label: | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | P22646 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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