Description
Product Name: | FGF1 Monoclonal Antibody |
Product Code: | CAB23167 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59565 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | U-2 OS, Mouse brain |
Cellular Location: | Cytoplasm, Nucleus, Secreted, cell cortex, cytosol |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-155 of human FGF1 (NP_000791.1). |
Sequence: | AEGEI TTFTA LTEKF NLPPG NYKKP KLLYC SNGGH FLRIL PDGTV DGTRD RSDQH IQLQL SAESV GEVYI KSTET GQYLA MDTDG LLYGS QTPNE ECLFL ERLEE NHYNT YISKK HAEKN WFVGL KKNGS CKRGP RTHYG QKAIL FLPLP VSSD |
Synonyms: | AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF-1, HBGF1, HBGF-1, GLIO703, ECGF-beta, FGF-alpha |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |