Fcgr3 Antibody (PACO34718)
- SKU:
- PACO34718
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Fcgr3 Antibody (PACO34718) |
| Antibody SKU: | PACO34718 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Low affinity immunoglobulin γ Fc region receptor III protein (31-215AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. |
| Synonyms: | Low affinity immunoglobulin γ Fc region receptor III (IgG Fc receptor III) (Fc-γ RIII) (FcRIII) (CD antigen CD16), Fcgr3 |
| UniProt Protein Function: | FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell surface; Receptor, misc. Cellular Component: external side of plasma membrane; integral to membrane; membrane; plasma membrane Molecular Function:IgG binding; IgG receptor activity Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; mast cell activation; neutrophil chemotaxis; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of type I hypersensitivity; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; regulation of immune response; serotonin secretion |
| UniProt Code: | P08508 |
| NCBI GenInfo Identifier: | 119877 |
| NCBI Gene ID: | 14131 |
| NCBI Accession: | P08508.1 |
| UniProt Related Accession: | P08508 |
| Molecular Weight: | |
| NCBI Full Name: | Low affinity immunoglobulin gamma Fc region receptor III |
| NCBI Synonym Full Names: | Fc receptor, IgG, low affinity III |
| NCBI Official Symbol: | Fcgr3 |
| NCBI Official Synonym Symbols: | CD16 |
| NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor III |
| UniProt Protein Name: | Low affinity immunoglobulin gamma Fc region receptor III |
| UniProt Synonym Protein Names: | Fc-gamma RIII; FcRIII; CD_antigen: CD16 |
| Protein Family: | CD160 antigen |
| UniProt Gene Name: | Fcgr3 |
| UniProt Entry Name: | FCGR3_MOUSE |
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