FBXL3 Polyclonal Antibody
- SKU:
- CAB14671
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | FBXL3 Polyclonal Antibody |
| Product Code: | CAB14671 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, HepG2 |
| Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human FBXL3 (NP_036290.1). |
| Sequence: | MKRGG RDSDR NSSEE GTAEK SKKLR TTNEH SQTCD WGNLL QDIIL QVFKY LPLLD RAHAS QVCRN WNQVF HMPDL WRCFE FELNQ PATSY LKATH PELIK QIIKR HSNHL |
| Synonyms: | FBL3, FBL3A, FBXL3A, IDDSFAS |
| Calculated MW: | 49kDa |
| Observed MW: | 55kDa |
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