Description
| Product Name: | FANCB Polyclonal Antibody |
| Product Code: | CAB21046 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | nucleoplasm |
This gene encodes a member of the Fanconi anemia complementation group B. This protein is assembled into a nucleoprotein complex that is involved in the repair of DNA lesions. Mutations in this gene can cause chromosome instability and VACTERL syndrome with hydrocephalus.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human FANCB (NP_001018123.1). |
| Sequence: | PSKSD YAIWN TKFCV YSLES QEVLS DIYII PPAYS SVVTY VHICA TEIIK NQLRI SLIAL TRKNQ LISFQ NGTPK NVCQL PFGDP CAVQL MDSGG GNLFF V |
| Synonyms: | FA2, FAB, FACB, FAAP90, FAAP95 |
| Calculated MW: | 98kDa |
| Observed MW: | Refer to figures |