EXOC2 Polyclonal Antibody
- SKU:
- CAB21568
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | EXOC2 Polyclonal Antibody |
| Product Code: | CAB21568 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | cytosol, exocyst, plasma membrane |
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human EXOC2 (NP_060773.3). |
| Sequence: | MSRSR QPPLV TGISP NEGIP WTKVT IRGEN LGTGP TDLIG LTICG HNCLL TAEWM SASKI VCRVG QAKND KGDII VTTKS GGRGT STVSF KLLKP EKIGI LDQSA VWVDE MNYYD MRTDR NKGIP PLSLR PANPL GIEIE KSKFS QKDLE MLFHG MSADF TSENF SAAWY LIENH SNTSF EQLKM AVTNL KRQAN KKSEG SLAYV KGGLS TFFEA QDALS |
| Synonyms: | SEC5, Sec5p, SEC5L1, NEDFACH |
| Calculated MW: | 104kDa |
| Observed MW: | Refer to figures |
Related Products
EXOC2 Monoclonal Antibody
![Anti-EXOC2 Antibody (CAB19948)[KO Validated]](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/56116/61298/anti-exoc2-antibody-cab19948ko-validated__63141__43031.1706533763.jpg?c=1 "Anti-EXOC2 Antibody (CAB19948)[KO Validated]")
Doublecortin Polyclonal Antibody
