EIF4A1/EIF4A2/EIF4A3 Monoclonal Antibody
- SKU:
- CAB24293
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | EIF4A1/EIF4A2/EIF4A3 Monoclonal Antibody |
| Product Code: | CAB24293 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56701 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:30000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, HeLa, C2C12, PC-12, Rat brain |
| Cellular Location: | Cytoplasm, Cytosol, Eukaryotic translation initiation factor 4F complex, Extracellular exosome |
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EIF4A1/EIF4A2/EIF4A3 (NP_001407.1/NP_001958.2/NP_055555.1). |
| Sequence: | MSASQ DSRSR DNGPD GMEPE GVIES NWNEI VDSFD DMNLS ESLLR GIYAY GFEKP SAIQQ RAILP CIKGY DVIAQ AQSGT GKTAT FAISI LQQIE LDLKA |
| Synonyms: | DDX2A, EIF4A, EIF-4A, eIF4A-I, eIF-4A-I, DDX2B, EIF4A, EIF4F, BM-010, eIF4A-II, eIF-4A-II, Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III |
| Calculated MW: | 46kDa |
| Observed MW: | 46kDa |
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