Description
Product Name: | ECE1 Polyclonal Antibody |
Product Code: | CAB21824 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Cell membrane, Single-pass type II membrane protein |
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 670-770 of human ECE1 (NP_001388.1). |
Sequence: | ADNGG LKAAY RAYQN WVKKN GAEHS LPTLG LTNNQ LFFLG FAQVW CSVRT PESSH EGLIT DPHSP SRFRV IGSLS NSKEF SEHFR CPPGS PMNPP HKCEV W |
Synonyms: | ECE |
Calculated MW: | 87kDa |
Observed MW: | Refer to figures |