DSG2 Polyclonal Antibody
- SKU:
- CAB21381
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DSG2 Polyclonal Antibody |
| Product Code: | CAB21381 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome |
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2). |
| Sequence: | CHCGK GAKGF TPIPG TIEML HPWNN EGAPP EDKVV PSFLP VDQGG SLVGR NGVGG MAKEA TMKGS SSASI VKGQH EMSEM DGRWE EHRSL LSGRA TQFTG ATGAI MTTET TKTAR ATGAS RDMAG AQAAA VALNE EFLRN YFTDK AASYT EEDEN HTAKD CLLVY SQEET ESLNA SIGCC SFIEG ELDDR FLDDL GLKFK TLAEV CLGQK IDINK EIEQR QKPAT ETSMN TASHS LCEQT MVNSE NTYSS GSSFP VPKSL QEANA EKVTQ EIVTE RSVSS RQAQK VATPL PDPMA SRNVI A |
| Synonyms: | HDGC, CDHF5 |
| Calculated MW: | 122kDa |
| Observed MW: | Refer to figures |
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