DGKA Monoclonal Antibody (CAB22202)

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SKU:
CAB22202
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC

Description

Product Name:DGKA Monoclonal Antibody
Product Code:CAB22202
Reactivity:Human
Applications:Western blotting, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC55770
Reactivity:Human
Tested Applications:WB, IHC-P, ELISA
Key Applications:Western blotting, Immunohistochemistry
Recommended Dilution:WB 1:2000-1:20000, IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat
Cellular Location:cytosol, plasma membrane

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DGKA (NP_001336.2).
Sequence:MAKER GLISP SDFAQ LQKYM EYSTK KVSDV LKLFE DGEMA KYVQG DAIGY EGFQQ FLKIY LEVDN VPRHL SLALF QSFET GHCLN ETNVT KDVVC LNDVS CYFSL LEGGR PEDKL EFTFK LYDTD RNGIL DSSEV DKIIL QMMRV AEYLD WDVSE LRPIL QEMMK EIDYD GSGSV SQAEW VRAGA TTVPL LVLLG LEMTL
Synonyms:DAGK, DAGK1, DGK-alpha
Calculated MW:83kDa
Observed MW:80kDa
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