DGKA Monoclonal Antibody (CAB22127)
- SKU:
- CAB22127
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DGKA Monoclonal Antibody |
| Product Code: | CAB22127 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55777 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Mouse lung, Rat lung |
| Cellular Location: | cytosol, plasma membrane |
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DGKA (NP_001336.2). |
| Sequence: | MAKER GLISP SDFAQ LQKYM EYSTK KVSDV LKLFE DGEMA KYVQG DAIGY EGFQQ FLKIY LEVDN VPRHL SLALF QSFET GHCLN ETNVT KDVVC LNDVS CYFSL LEGGR PEDKL EFTFK LYDTD RNGIL DSSEV DKIIL QMMRV AEYLD WDVSE LRPIL QEMMK EIDYD GSGSV SQAEW VRAGA TTVPL LVLLG LEMTL |
| Synonyms: | DAGK, DAGK1, DGK-alpha |
| Calculated MW: | 83kDa |
| Observed MW: | 80kDa |
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