Cynomolgus CD40L Receptor Recombinant Protein (RPES3174)
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- SKU:
- RPES3174
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Description
system_update_altDatasheet
Cynomolgus CD40L Receptor Recombinant Protein
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction.
| Product Name: | Cynomolgus CD40L Receptor Recombinant Protein (RPES3174) |
| Product Code: | RPES3174 |
| Size: | 10µg |
| Species: | Cynomolgus |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor Necrosis Factor Receptor Superfamily member 5, B-Cell Surface Antigen CD40, Bp50, CD40L Receptor, CDw40, CD40, TNFRSF5 |
| Accession: | G7PG38 |
| Sequence: | Glu21-Arg193 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Cynomolgus CD40 is produced by our Mammalian expression system and the target gene encoding Glu21-Arg193 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 46.3 kDa |
| AP Mol Mass: | 30&35&60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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