Cynomolgus CD38 Recombinant Protein (RPES3252)
- SKU:
- RPES3252
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Description
system_update_altDatasheet
Cynomolgus CD38 Recombinant Protein
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
| Product Name: | Cynomolgus CD38 Recombinant Protein (RPES3252) |
| Product Code: | RPES3252 |
| Size: | 10µg |
| Species: | Cynomolgus |
| Expressed Host: | Human Cells |
| Synonyms: | ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase,CD38,T10 |
| Accession: | Q5VAN0 |
| Sequence: | Leu44-Ile301 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 30.9 kDa |
| AP Mol Mass: | 38-50 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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