Description
Product Name: | Cullin 1 Polyclonal Antibody |
Product Code: | CAB21687 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:100-1:500, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | Mouse brain, Rat brain |
Cellular Location: | cytosol, nucleoplasm, plasma membrane |
Predicted to enable ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Located in plasma membrane. Part of Parkin-FBXW7-Cul1 ubiquitin ligase complex and SCF ubiquitin ligase complex.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 435-593 of human Cullin 1 (NP_003583.2). |
Sequence: | KNPEE AELED TLNQV MVVFK YIEDK DVFQK FYAKM LAKRL VHQNS ASDDA EASMI SKLKQ ACGFE YTSKL QRMFQ DIGVS KDLNE QFKKH LTNSE PLDLD FSIQV LSSGS WPFQQ SCTFA LPSEL ERSYQ RFTAF YASRH SGRKL TWLYQ LSKGE LVTN |
Synonyms: | CUL1, MGC149834, MGC149835, cullin-1 |
Calculated MW: | 90kDa |
Observed MW: | 90kDa |