Description
Product Name: | CSNK2A2 Polyclonal Antibody |
Product Code: | CAB21368 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Positive Samples: | 293T, HeLa, K-562 |
Cellular Location: | acrosomal vesicle, cytosol, nucleoplasm, nucleus, plasma membrane |
Customer Validation: | WB(Homo sapiens) |
This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CSNK2A2 (NP_001887.1). |
Sequence: | MPGPA AGSRA RVYAE VNSLR SREYW DYEAH VPSWG NQDDY QLVRK LGRGK YSEVF EAINI TNNER VVVKI LKPVK KKKIK REVKI LENLR GGTNI IKLID TVKDP VSKTP ALVFE YINNT DFKQL YQILT DFDIR FYMYE LLKAL DYCHS KGIMH RDVKP HNVMI DHQQK KLRLI DWGLA EFYHP AQEYN VRVAS RYFKG PELLV DYQMY DYSLD MWSLG CMLAS MIFRR EPFFH GQDNY DQLVR IAKVL GTEEL YGYLK KYHID LDPHF NDILG QHSRK RWENF IHSEN RHLVS PEALD LLDKL LRYDH QQRLT AKEAM EHPYF YPVVK EQSQP CADNA VLSSG LTAAR |
Synonyms: | CK2A2, CSNK2A1, CK2alpha' |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |